SCHEMBL3487387

SCHEMBL3487387

O=C(O)CC(S)N1C(=O)CCC1=O

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.44
ATM Q13315 1/20 0.44
ALDH1A1 P00352 1/20 0.40
PKM P14618 1/20 0.40
SLC1A2 P43004 1/20 0.35
SLC22A6 Q4U2R8 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28393846 0.85 ALDH1A1 (0.37) KMT2AATMALDH1A1PKMSLC1A2
SCHEMBL9254263 0.80 KMT2A (0.42) KMT2AATMALDH1A1PKMSLC1A2
SCHEMBL3801263 0.78 KMT2A (0.46) KMT2AATMALDH1A1PKMSLC1A2
SCHEMBL2332165 0.75 ALDH1A1 (0.56) KMT2AATMALDH1A1PKMSLC1A2
SCHEMBL1564210 0.75 KMT2A (0.47) KMT2AATMALDH1A1PKMSLC1A2
SCHEMBL604671 0.75 ALDH1A1 (0.56) KMT2AATMALDH1A1PKMSLC1A2
SCHEMBL454926 0.75 KMT2A (0.41) KMT2AATMALDH1A1PKMSLC1A2
SCHEMBL9607 0.73 KMT2A (0.43) KMT2AATMALDH1A1PKMSLC1A2
SCHEMBL9856992 0.73 LMNA (0.47) KMT2AATMALDH1A1TDP1TSHR
SCHEMBL30302184 0.72 ALDH1A1 (0.53) KMT2AATMALDH1A1PKMSLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210041427-A1 METHODS AND COMPOSITIONS FOR PHOTOTRANSFER AMBERGEN, INC 2021-02-11 US disclosed
US-10088474-B2 Methods and compositions for phototransfer AMBERGEN, INC. (US) 2018-10-02 US disclosed
US-9910034-B2 Methods and compositions for phototransfer AMBERGEN, INC. (US) 2018-03-06 US disclosed
US-20180017550-A1 METHODS AND COMPOSITIONS FOR PHOTOTRANSFER AMBERGEN, INC. 2018-01-18 US disclosed
US-20160313313-A1 LATERAL FLOW ASSAY APPARATUS AND METHOD, AND SENSOR THERFOR THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2016-10-27 US disclosed
US-20160139113-A1 Methods and Compositions for Phototransfer AMBERGEN, INC. 2016-05-19 US disclosed
US-9334530-B2 Methods for making and imaging arrays that comprise a plurality of different biomolecules AMBERGEN, INC. (US) 2016-05-10 US disclosed
US-20160018396-A1 Methods and Compositions for Phototransfer AMBERGEN, INC. 2016-01-21 US disclosed
WO-2015106331-A1 LATERAL FLOW ASSAY APPARATUS AND METHOD, AND SENSOR THEREFOR HER MAJESTY THE QUEEN IN RIGHT OF CANADA, AS REPRESENTED BY THE MINISTER OF NATIONAL DEFENCE (CA) 2015-07-23 WO disclosed
US-20150192577-A1 Methods and Compositions for Phototransfer AMBERGEN, INC. 2015-07-09 US disclosed
US-20100317542-A1 Methods For Detecting Biomarkers AMBERGEN, INC. 2010-12-16 US disclosed
US-20100311042-A1 Amplifying bisulfite-treated template AMBERGEN, INC. 2010-12-09 US disclosed
US-20100256015-A1 Methods For Making And Imaging Arrays AMBERGEN, INC. 2010-10-07 US disclosed
US-20100203651-A1 Methods and compounds for phototransfer AMBERGEN, INC. 2010-08-12 US disclosed
US-20100075374-A1 Methods for capturing nascent proteins AMBERGEN, INC. 2010-03-25 US disclosed
US-20100062451-A1 Bead-ligand-nascent protein complexes AMBERGEN, INC. 2010-03-11 US disclosed
US-20090286286-A1 Methods for controlling amplification AMBERGEN , INC. 2009-11-19 US disclosed
US-20090270278-A1 Methods and compounds for making arrays AMBERGEN, INC. 2009-10-29 US disclosed
US-20090264298-A1 Methods for enriching subpopulations AMBERGEN, INC. 2009-10-22 US disclosed
WO-2009061402-A2 METHODS AND COMPOUNDS FOR PHOTOTRANSFER AMBERGEN, INC. (US) 2009-05-14 WO disclosed