Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 4/20 | 0.67 |
| ▸ | DGKI | O75912 | 3/20 | 0.67 |
| ▸ | DGKZ | Q13574 | 3/20 | 0.67 |
| ▸ | DGKG | P49619 | 2/20 | 0.59 |
| ▸ | DGKB | Q9Y6T7 | 2/20 | 0.59 |
| ▸ | DGKK | Q5KSL6 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23293232 | 0.89 | DGKA (0.84) | DGKADGKIDGKZDGKGDGKB | |
| SCHEMBL30616710 | 0.84 | DGKA (0.82) | DGKADGKIDGKZDGKGDGKB | |
| SCHEMBL29137195 | 0.84 | DGKA (0.62) | DGKADGKIDGKZDGKGDGKB | |
| SCHEMBL30616441 | 0.84 | DGKZ (0.68) | DGKADGKIDGKZDGKGDGKB | |
| SCHEMBL23293283 | 0.84 | DGKZ (0.68) | DGKADGKIDGKZDGKGDGKB | |
| SCHEMBL23293213 | 0.80 | DGKA (1.00) | DGKADGKIDGKZDGKGDGKB | |
| SCHEMBL23293420 | 0.80 | DGKA (0.68) | DGKADGKIDGKZDGKGDGKB | |
| SCHEMBL30616467 | 0.80 | DGKA (1.00) | DGKADGKIDGKZDGKGDGKB | |
| SCHEMBL23293125 | 0.80 | DGKA (0.67) | DGKADGKIDGKZDGKGDGKB | |
| SCHEMBL30616748 | 0.79 | DGKA (0.86) | DGKADGKIDGKZDGKGDGKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585139-B | Naphthyridinone compounds as T cell activators | 百时美施贵宝公司 | 2023-12-01 | — | — | CN | disclosed |