Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 11/20 | 0.61 |
| ▸ | DGKZ | Q13574 | 10/20 | 0.61 |
| ▸ | DGKI | O75912 | 3/20 | 0.61 |
| ▸ | DGKG | P49619 | 2/20 | 0.61 |
| ▸ | DGKB | Q9Y6T7 | 2/20 | 0.61 |
| ▸ | DGKK | Q5KSL6 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GNRHR | P30968 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137245 | 0.92 | DGKA (0.59) | DGKADGKZDGKIDGKGDGKB | |
| SCHEMBL23293219 | 0.87 | DGKA (0.65) | DGKADGKZDGKIDGKGDGKB | |
| SCHEMBL23293265 | 0.85 | DGKA (0.84) | DGKADGKZDGKIDGKGDGKB | |
| SCHEMBL30422576 | 0.82 | DGKZ (0.76) | DGKADGKZDGKIDGKGDGKB | |
| SCHEMBL23293563 | 0.82 | DGKZ (0.76) | DGKADGKZDGKIDGKGDGKB | |
| SCHEMBL23293323 | 0.82 | DGKA (0.64) | DGKADGKZDGKIDGKGDGKB | |
| SCHEMBL23293506 | 0.80 | DGKA (0.81) | DGKADGKZDGKIDGKGDGKB | |
| SCHEMBL23293415 | 0.78 | DGKA (0.78) | DGKADGKZDGKIDGKGDGKB | |
| SCHEMBL23293504 | 0.78 | DGKA (0.64) | DGKADGKZDGKIDGKGDGKB | |
| SCHEMBL23293461 | 0.77 | DGKA (0.76) | DGKADGKZDGKIDGKGDGKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585139-B | Naphthyridinone compounds as T cell activators | 百时美施贵宝公司 | 2023-12-01 | — | — | CN | disclosed |