Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 3/20 | 0.45 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | FABP1 | P07148 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23293231 | 0.80 | PKM (0.54) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL5369302 | 0.78 | CYP3A4 (0.59) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| SCHEMBL28549221 | 0.74 | TSHR (0.47) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL8767072 | 0.73 | TSHR (0.63) | ALDH1A1MEN1KMT2ATSHRHTT | |
| SCHEMBL8903216 | 0.71 | TSHR (0.66) | ALDH1A1MEN1KMT2ATSHRHTT | |
| SCHEMBL19375077 | 0.71 | TSHR (0.66) | ALDH1A1MEN1KMT2ATSHRHTT | |
| SCHEMBL14818738 | 0.71 | TSHR (0.71) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL10261881 | 0.71 | CYP2C19 (0.62) | ALDH1A1MEN1KMT2AHTTLMNA | |
| SCHEMBL28061777 | 0.70 | CYP3A4 (0.50) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| SCHEMBL8514786 | 0.70 | TSHR (0.75) | ALDH1A1MEN1KMT2ATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585139-B | Naphthyridinone compounds as T cell activators | 百时美施贵宝公司 | 2023-12-01 | — | — | CN | disclosed |