Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30184323 | 1.00 | ALDH1A1 (0.51) | ALDH1A1GAACYP3A4TSHRTDP1 | |
| SCHEMBL30871334 | 0.83 | ALDH1A1 (0.54) | ALDH1A1CYP3A4TSHRTDP1KMT2A | |
| SCHEMBL3801116 | 0.83 | ALDH1A1 (0.54) | ALDH1A1CYP3A4TSHRTDP1KMT2A | |
| SCHEMBL309800 | 0.82 | ALDH1A1 (0.53) | ALDH1A1GAACYP3A4TSHRTDP1 | |
| SCHEMBL6990289 | 0.81 | MAPT (0.53) | ALDH1A1GAACYP3A4TSHRTDP1 | |
| SCHEMBL310574 | 0.80 | VCAM1 (0.58) | ALDH1A1CYP3A4TSHRTDP1KMT2A | |
| SCHEMBL3107502 | 0.80 | PRMT5 (0.56) | ALDH1A1CYP3A4TSHRTDP1KMT2A | |
| SCHEMBL3245238 | 0.79 | MAPT (0.55) | ALDH1A1GAACYP3A4TSHRTDP1 | |
| SCHEMBL3237446 | 0.79 | MEN1 (0.57) | ALDH1A1GAACYP3A4TSHRTDP1 | |
| SCHEMBL15880765 | 0.78 | HTT (0.46) | ALDH1A1GAACYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116870016-B | Heteroaromatic compound and medical application thereof | 希格生科（深圳）有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117412981-A | Phosphine oxide derivative and preparation method and application thereof | 希格生科（深圳）有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-116870016-A | Heteroaromatic compound and medical application thereof | 希格生科（深圳）有限公司 | 2023-10-13 | — | — | CN | disclosed |