Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626668 | 0.75 | BCHE (0.40) | BCHEACHE | |
| SCHEMBL9073078 | 0.73 | BCHE (0.38) | BCHEACHE | |
| SCHEMBL9070211 | 0.72 | BCHE (0.37) | BCHEACHEGPR3 | |
| SCHEMBL31619967 | 0.71 | BCHE (0.39) | BCHEACHEPTPN1GPR3 | |
| SCHEMBL9073633 | 0.71 | BCHE (0.34) | BCHEACHE | |
| SCHEMBL9073547 | 0.71 | BCHE (0.34) | BCHEACHE | |
| SCHEMBL8752750 | 0.71 | GPR3 (0.54) | ACHELIPGGPR3 | |
| SCHEMBL8752773 | 0.71 | LIPG (0.47) | BCHEACHECYSLTR2CYSLTR1LIPG | |
| SCHEMBL8752769 | 0.71 | SLC6A2 (0.53) | ACHELIPGGPR3 | |
| SCHEMBL8752749 | 0.71 | LIPG (0.47) | CYSLTR2CYSLTR1LIPGNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114073688-B | Application of 2, 3-diaryl derivative in preparing medicament for treating liver related diseases | 中国医学科学院药物研究所 | 2024-02-06 | — | — | CN | disclosed |
| CN-114075102-B | 2, 3-diaryl indene derivative, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-01-12 | — | — | CN | disclosed |