Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 10/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NPR3 | P17342 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 2/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137721 | 0.89 | CAMK2D (0.40) | BRAFVNN1HDAC3HDAC1HDAC2 | |
| SCHEMBL29137741 | 0.82 | EZH2 (0.38) | BRAFVNN1HDAC3HDAC1HDAC2 | |
| SCHEMBL29137743 | 0.82 | EZH2 (0.39) | BRAFVNN1HDAC3HDAC1HDAC2 | |
| SCHEMBL30768169 | 0.80 | NPC1 (0.41) | BRAFCYP1A2CYP3A4CYP2C19PLK1 | |
| SCHEMBL23169690 | 0.77 | PCSK9 (0.31) | — | |
| SCHEMBL32661517 | 0.77 | AURKA (0.34) | BRAF | |
| SCHEMBL32662613 | 0.74 | BRD4 (0.42) | HDAC1 | |
| SCHEMBL31563705 | 0.74 | BRD4 (0.42) | HDAC1 | |
| SCHEMBL23169315 | 0.73 | EZH2 (0.50) | ADORA2AADORA2B | |
| SCHEMBL32661546 | 0.72 | ACACB (0.37) | BRAFVNN1HDAC3HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384153-A | Methyltransferase inhibitors and uses thereof | 上海赛岚生物科技有限公司 | 2024-01-12 | — | — | CN | disclosed |