Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 7/20 | 0.37 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137721 | 0.90 | CAMK2D (0.40) | BRAFCAMK2DVNN1HDAC3HDAC1 | |
| SCHEMBL29137741 | 0.87 | EZH2 (0.38) | EZH2BRAFLRRK2VNN1IDH1 | |
| SCHEMBL29137722 | 0.82 | BRAF (0.39) | BRAFVNN1HDAC3HDAC1HDAC2 | |
| SCHEMBL32661517 | 0.79 | AURKA (0.34) | BRAFCAMK2D | |
| SCHEMBL29137720 | 0.78 | EZH2 (0.55) | EZH2BRAFLRRK2VNN1 | |
| SCHEMBL30768169 | 0.75 | NPC1 (0.41) | BRAFIDH1 | |
| SCHEMBL30768170 | 0.70 | MEN1 (0.38) | EZH2BRAFVNN1HDAC3HDAC1 | |
| SCHEMBL23169460 | 0.69 | EZH2 (0.61) | EZH2VNN1 | |
| SCHEMBL23169459 | 0.69 | EZH2 (0.53) | EZH2 | |
| SCHEMBL32661546 | 0.68 | ACACB (0.37) | EZH2BRAFVNN1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384153-A | Methyltransferase inhibitors and uses thereof | 上海赛岚生物科技有限公司 | 2024-01-12 | — | — | CN | disclosed |