Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137736 | 1.00 | APP (0.41) | APPHDAC1HDAC6AAK1AKR1C3 | |
| SCHEMBL29137717 | 0.88 | HDAC1 (0.40) | APPHDAC1HDAC6AKR1C3AKR1C2 | |
| SCHEMBL30768173 | 0.81 | HDAC1 (0.39) | APPHDAC1HDAC6AKR1C3AKR1C2 | |
| SCHEMBL29137719 | 0.81 | HDAC1 (0.39) | APPHDAC1HDAC6AKR1C3AKR1C2 | |
| SCHEMBL29137726 | 0.79 | ATM (0.41) | APPAKR1C3AKR1C2MAPTALDH1A1 | |
| SCHEMBL29137724 | 0.79 | ATM (0.41) | APPAKR1C3AKR1C2MAPTALDH1A1 | |
| SCHEMBL8282320 | 0.72 | ALDH1A1 (0.43) | APPHDAC1HDAC6AKR1C2MAPT | |
| SCHEMBL4826032 | 0.71 | ALDH1A1 (0.52) | HDAC1HDAC6MAPTNPC1RAB9A | |
| SCHEMBL355461 | 0.70 | HDAC1 (0.51) | HDAC1HDAC6MAPTNPC1RAB9A | |
| SCHEMBL13172090 | 0.69 | AKR1C3 (0.47) | APPHDAC1HDAC6AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260015352-A1 | METHYLTRANSFERASE INHIBITOR AND USE THEREOF | CYTOSINLAB THERAPEUTICS CO LTD (CN) | 2026-01-15 | — | — | US | disclosed |
| CN-119923393-A | Methyltransferase inhibitors and uses thereof | 上海赛岚生物科技有限公司 | 2025-05-02 | — | — | CN | disclosed |
| WO-2024012461-A1 | METHYLTRANSFERASE INHIBITOR AND USE THEREOF | 上海赛岚生物科技有限公司 | 2024-01-18 | — | — | WO | disclosed |
| CN-117384153-A | Methyltransferase inhibitors and uses thereof | 上海赛岚生物科技有限公司 | 2024-01-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260015352-A1 | METHYLTRANSFERASE INHIBITOR AND USE THEREOF | EZH2, DOT1L, EHMT1 | APP 4350/4885HDAC1 32/4885HDAC6 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.