Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.37 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 3/20 | 0.34 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15806743 | 0.81 | PYCR1 (0.47) | DGAT1PYCR1KDM1AKDM1BNPC1 | |
| SCHEMBL31448605 | 0.81 | PYCR1 (0.47) | DGAT1PYCR1KDM1AKDM1BNPC1 | |
| SCHEMBL138081 | 0.81 | DPP4 (0.41) | DPP4BRD4BRD2BRD3BRDT | |
| SCHEMBL1106603 | 0.79 | CCR5 (0.45) | DPP4BRD4BRD2BRD3BRDT | |
| SCHEMBL20560539 | 0.79 | DPP4 (0.40) | DPP4BRD4BRD2BRD3BRDT | |
| SCHEMBL15352101 | 0.79 | DPP4 (0.40) | DPP4BRD4BRD2BRD3BRDT | |
| SCHEMBL6998004 | 0.79 | DPP4 (0.40) | DPP4BRD4BRD2BRD3BRDT | |
| SCHEMBL135165 | 0.79 | PTGDR2 (0.49) | DPP4BRD4BRD2BRD3BRDT | |
| SCHEMBL30138589 | 0.79 | BRD4 (0.42) | DPP4BRD4BRD2BRD3BRDT | |
| SCHEMBL3074139 | 0.79 | BRD4 (0.42) | DPP4BRD4BRD2BRD3BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117062804-A | 1, 3-substituted cyclobutyl derivatives and their use | 诺华股份有限公司 | 2023-11-14 | — | — | CN | disclosed |