Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
| ▸ | POLG | P54098 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5942534 | 0.96 | POLB (0.47) | POLBABCB11POLA1POLGFAP | |
| SCHEMBL2907893 | 0.89 | FAP (0.41) | POLBABCB11POLA1POLGFAP | |
| SCHEMBL2905699 | 0.88 | FAP (0.45) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2913623 | 0.88 | FAP (0.49) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2912371 | 0.88 | FAP (0.45) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2910965 | 0.87 | ABCB11 (0.44) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2911382 | 0.86 | FAP (0.46) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2912615 | 0.86 | FAP (0.43) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2911205 | 0.85 | FAP (0.43) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2912516 | 0.85 | FAP (0.43) | ABCB11POLA1POLGFAPSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | disclosed |