Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 9/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4540142 | 0.81 | AKR1B1 (0.58) | AKR1B1 | |
| SCHEMBL22494209 | 0.80 | AKR1B1 (0.35) | AKR1B1 | |
| SCHEMBL29236467 | 0.78 | AKR1B1 (0.41) | AKR1B1 | |
| SCHEMBL27534224 | 0.78 | AKR1B1 (0.60) | AKR1B1 | |
| SCHEMBL1763273 | 0.78 | AKR1B1 (0.60) | AKR1B1 | |
| SCHEMBL4730663 | 0.73 | AKR1B1 (0.33) | AKR1B1 | |
| SCHEMBL818508 | 0.72 | HTR6 (0.50) | — | |
| SCHEMBL28977117 | 0.69 | AKR1B1 (0.64) | AKR1B1 | |
| SCHEMBL27407696 | 0.69 | AKR1B1 (0.42) | AKR1B1 | |
| SCHEMBL28085263 | 0.69 | AKR1B1 (0.41) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343011-A | Compound based on pyrazolyl-sulfonyl-phenyl skeleton structure, its preparation method and application, and pharmaceutical composition | 晨伫(杭州)生物科技有限责任公司 | 2024-01-05 | — | — | CN | claimed |
| CN-117343011-A | Compound based on pyrazolyl-sulfonyl-phenyl skeleton structure, its preparation method and application, and pharmaceutical composition | 晨伫(杭州)生物科技有限责任公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-117343011-A | Compound based on pyrazolyl-sulfonyl-phenyl skeleton structure, its preparation method and application, and pharmaceutical composition | 晨伫(杭州)生物科技有限责任公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-117343011-A | Compound based on pyrazolyl-sulfonyl-phenyl skeleton structure, its preparation method and application, and pharmaceutical composition | 晨伫(杭州)生物科技有限责任公司 | 2024-01-05 | — | — | CN | disclosed |