Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 8/20 | 0.58 |
| ▸ | HTR6 | P50406 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22494209 | 0.83 | AKR1B1 (0.35) | AKR1B1 | |
| SCHEMBL29236467 | 0.81 | AKR1B1 (0.41) | AKR1B1HTR6ALDH1A1TSHR | |
| SCHEMBL27534224 | 0.81 | AKR1B1 (0.60) | AKR1B1 | |
| SCHEMBL29138001 | 0.81 | AKR1B1 (0.39) | AKR1B1 | |
| SCHEMBL1763273 | 0.81 | AKR1B1 (0.60) | AKR1B1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL27407695 | 0.79 | AKR1B1 (0.42) | AKR1B1HTR6ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL27407696 | 0.79 | AKR1B1 (0.42) | AKR1B1HTR6FEN1 | |
| SCHEMBL28085263 | 0.79 | AKR1B1 (0.41) | AKR1B1 | |
| SCHEMBL28977117 | 0.79 | AKR1B1 (0.64) | AKR1B1HTR6TDP1TSHRSMN1; SMN2 | |
| SCHEMBL27393119 | 0.76 | KDM4E (0.49) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107556255-A | A kind of organic amine modified melamine polyphosphate and preparation method thereof | 东华大学 | 2018-01-09 | — | — | CN | claimed |
| CN-107459492-A | A kind of organically-modified melamine polyphosphate and preparation method thereof | 东华大学 | 2017-12-12 | — | — | CN | claimed |
| JP-1221368-A | — | — | None | — | — | JP | disclosed |
| CN-114411178-B | Polysubstituted pyrazole compound and electrochemical synthesis method thereof | 南京工业大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-114411178-A | Polysubstituted pyrazole compound and electrochemical synthesis method thereof | 南京工业大学 | 2022-04-29 | — | — | CN | disclosed |
| CN-107556255-A | A kind of organic amine modified melamine polyphosphate and preparation method thereof | 东华大学 | 2018-01-09 | — | — | CN | disclosed |
| CN-107459492-A | A kind of organically-modified melamine polyphosphate and preparation method thereof | 东华大学 | 2017-12-12 | — | — | CN | disclosed |
| US-7622486-B2 | Pyridine compounds, process for their preparation and compositions containing them | REDDY US THERAPEUTICS, INC. (US) | 2009-11-24 | — | — | US | disclosed |
| CN-101331118-A | Pyrazoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2008-12-24 | — | — | CN | disclosed |
| WO-2007129169-A2 | COX- II INHIBITORS FOR IMPROVING REPRODUCTIVE SUCCESS IN A FEMALE ANIMAL | PFIZER LIMITED (GB) | 2007-11-15 | — | — | WO | disclosed |
| US-20060084644-A1 | Novel pyridine compounds, process for their preparation and compositions containing them | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-04-20 | — | — | US | disclosed |
| JP-H01221368-A | PHENYLSULFONYLPYRAZOLE DERIVATIVE | DAI ICHI SEIYAKU CO LTD | 1989-09-04 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084644-A1 | Novel pyridine compounds, process for their preparation and compositions containing them | LDLR, LRP6, PLPBP | AKR1B1 2042/4885HTR6 3178/4885ALDH1A1 3749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.