Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.50 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27351526 | 1.00 | MAPT (0.54) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL29092879 | 0.83 | GLA (0.56) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL28968012 | 0.83 | GLA (0.56) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| Hydrochloric Acid SCHEMBL7159043 | 0.81 | MEN1 (0.51) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5809632 | 0.79 | LMNA (0.50) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL1070871 | 0.79 | GLA (0.55) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL1949533 | 0.77 | HTT (0.70) | MAPTRAB9ANPC1LMNAALDH1A1 | |
| SCHEMBL21249070 | 0.77 | KMT2A (0.54) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL1949534 | 0.77 | HTT (0.70) | MAPTRAB9ANPC1LMNAALDH1A1 | |
| SCHEMBL28013948 | 0.77 | MAPT (0.58) | MAPTRAB9ANPC1NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115322157-B | Letermopevir intermediate compound, preparation method and application thereof | 浙江车头制药股份有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-115322157-A | Letemovir intermediate compound and preparation method and application thereof | 浙江车头制药股份有限公司 | 2022-11-11 | — | — | CN | disclosed |