Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.88 |
| ▸ | MTNR1B | P49286 | 17/20 | 0.88 |
| ▸ | NQO2 | P16083 | 3/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30669508 | 1.00 | MTNR1A (0.88) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL9304037 | 0.94 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL9751553 | 0.89 | MTNR1A (0.79) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8686010 | 0.87 | MTNR1A (0.77) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL31543684 | 0.86 | MTNR1A (0.75) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL31543721 | 0.84 | MTNR1A (0.72) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL3645985 | 0.83 | MTNR1A (0.71) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL31530479 | 0.82 | MTNR1A (0.78) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL31530480 | 0.82 | MTNR1A (0.78) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL8946916 | 0.82 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069645-A | Tryptophan and C2 alkylation modification method for tryptophan-containing polypeptide | 兰州大学 | 2023-11-17 | — | — | CN | disclosed |