Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.79 |
| ▸ | MTNR1B | P49286 | 17/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.79 |
| ▸ | HPGD | P15428 | 3/20 | 0.79 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.79 |
| ▸ | TSHR | P16473 | 2/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401128 | 0.89 | MTNR1A (0.64) | MTNR1AMTNR1BCYP1A2CYP3A4HPGD | |
| SCHEMBL29138500 | 0.89 | MTNR1A (0.88) | MTNR1AMTNR1BCYP1A2CYP3A4HPGD | |
| SCHEMBL30669508 | 0.89 | MTNR1A (0.88) | MTNR1AMTNR1BCYP1A2CYP3A4HPGD | |
| Luzindole SCHEMBL4869000 | 0.88 | MTNR1A (1.00) | MTNR1AMTNR1BCYP1A2CYP3A4HPGD | |
| SCHEMBL9401161 | 0.87 | MTNR1A (0.84) | MTNR1AMTNR1BCYP1A2CYP3A4HPGD | |
| SCHEMBL29138489 | 0.87 | MTNR1A (0.60) | MTNR1AMTNR1BCYP1A2CYP3A4HPGD | |
| SCHEMBL9304037 | 0.87 | MTNR1A (1.00) | MTNR1AMTNR1BCYP1A2CYP3A4HPGD | |
| SCHEMBL7692306 | 0.80 | KDM4E (0.56) | MTNR1AMTNR1BCYP1A2CYP3A4HPGD | |
| Luzindole SCHEMBL9118261 | 0.80 | MEN1 (0.81) | MTNR1AMTNR1BCYP1A2CYP3A4HPGD | |
| SCHEMBL29138511 | 0.79 | MTNR1A (0.52) | MTNR1AMTNR1BCYP1A2CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069645-A | Tryptophan and C2 alkylation modification method for tryptophan-containing polypeptide | 兰州大学 | 2023-11-17 | — | — | CN | disclosed |
| EP-0375726-A4 | MELATONIN ANALOGUES | — | 1991-01-30 | — | — | EP | disclosed |
| EP-0375726-A1 | MELATONIN ANALOGUES | Whitby Research Incorporated (US) | 1990-07-04 | — | — | EP | disclosed |
| WO-1989001472-A1 | MELATONIN ANALOGUES | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1989-02-23 | — | — | WO | disclosed |