Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | DRD2 | P14416 | 3/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.56 |
| ▸ | HTR3B | O95264 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.56 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564312 | 0.86 | MAPT (0.56) | MAPTALDH1A1HPGDDRD2DRD3 | |
| SCHEMBL1681827 | 0.81 | DRD2 (0.64) | MAPTALDH1A1HPGDDRD2DRD3 | |
| SCHEMBL30720573 | 0.79 | DRD2 (0.66) | MAPTALDH1A1HPGDDRD2DRD3 | |
| Ethylene SCHEMBL7715815 | 0.79 | DRD2 (0.60) | MAPTALDH1A1HPGDDRD2DRD3 | |
| SCHEMBL4794209 | 0.78 | DRD2 (0.69) | MAPTALDH1A1HPGDDRD2DRD3 | |
| SCHEMBL27728800 | 0.78 | DRD2 (0.54) | MAPTALDH1A1HPGDDRD2DRD3 | |
| SCHEMBL30407688 | 0.76 | DRD2 (0.72) | MAPTALDH1A1HPGDDRD2DRD3 | |
| SCHEMBL3165674 | 0.76 | DRD2 (0.72) | MAPTALDH1A1HPGDDRD2DRD3 | |
| SCHEMBL29138522 | 0.76 | DRD2 (0.67) | MAPTALDH1A1HPGDDRD2DRD3 | |
| SCHEMBL10998253 | 0.75 | DRD2 (0.62) | MAPTALDH1A1HPGDDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069720-A | 5-HT 2A Receptor agonist, preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-11-17 | — | — | CN | disclosed |