Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30837129 | 0.89 | KDM4E (0.40) | PDE9ASLC6A9KDM4ELMNAABL1 | |
| SCHEMBL29138897 | 0.89 | KDM4E (0.40) | PDE9ASLC6A9KDM4ELMNAABL1 | |
| SCHEMBL29138945 | 0.89 | KDM4E (0.40) | PDE9ASLC6A9KDM4ELMNAABL1 | |
| SCHEMBL28818452 | 0.85 | LMNA (0.41) | PDE9AKDM4ELMNAABL1KMT2A | |
| SCHEMBL29852305 | 0.77 | KMT2A (0.42) | PDE9AKDM4ELMNAABL1KMT2A | |
| SCHEMBL16452781 | 0.77 | KMT2A (0.42) | PDE9AKDM4ELMNAABL1KMT2A | |
| SCHEMBL31308042 | 0.76 | KDM4C (0.31) | — | |
| SCHEMBL28580878 | 0.76 | HTR2C (0.47) | — | |
| SCHEMBL29844008 | 0.75 | HCRTR1 (0.58) | KDM4ELMNAABL1HCRTR1HCRTR2 | |
| SCHEMBL28131310 | 0.74 | ALOX5AP (0.43) | PDE9AKDM4ELMNAABL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888120-A | PRMTS inhibitors | 美国安进公司 | 2023-10-13 | — | — | CN | disclosed |