Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PDE9A | O76083 | 1/20 | 0.38 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29138897 | 1.00 | KDM4E (0.40) | KDM4EABL1LMNAPDE9AMAP3K12 | |
| SCHEMBL30837129 | 1.00 | KDM4E (0.40) | KDM4EABL1LMNAPDE9AMAP3K12 | |
| SCHEMBL28818452 | 0.92 | LMNA (0.41) | KDM4EABL1LMNAPDE9AADRA2A | |
| SCHEMBL29138936 | 0.89 | PDE9A (0.41) | KDM4EABL1LMNAPDE9AGPR119 | |
| SCHEMBL28721938 | 0.79 | HSD11B1 (0.39) | DPP4 | |
| SCHEMBL29138789 | 0.79 | ADRA2A (0.49) | ADRA2ADRD1DRD5ADRA1BP2RY14 | |
| SCHEMBL28818450 | 0.79 | ADRA2A (0.49) | ADRA2ADRD1DRD5ADRA1BP2RY14 | |
| SCHEMBL16452781 | 0.76 | KMT2A (0.42) | KDM4EABL1LMNAPDE9AGPR119 | |
| SCHEMBL29852305 | 0.76 | KMT2A (0.42) | KDM4EABL1LMNAPDE9AGPR119 | |
| SCHEMBL21037760 | 0.76 | KCNH2 (0.47) | KDM4EABL1LMNAMAP3K12GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888120-A | PRMTS inhibitors | 美国安进公司 | 2023-10-13 | — | — | CN | disclosed |