Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 16/20 | 0.43 |
| ▸ | PGR | P06401 | 10/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL450470 | 0.76 | NR3C1 (0.73) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3684073 | 0.71 | NR3C1 (0.42) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL1932525 | 0.70 | NR3C1 (0.58) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL5521098 | 0.68 | NR3C1 (0.39) | NR3C1NR3C2PGR | |
| SCHEMBL10313415 | 0.67 | NR3C1 (0.69) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL292335 | 0.67 | NR3C1 (0.69) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL5936548 | 0.66 | NR3C2 (0.39) | NR3C1NR3C2PGR | |
| SCHEMBL14340546 | 0.65 | NR3C1 (0.71) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL14163720 | 0.64 | NR3C1 (0.42) | NR3C1NR3C2PGR | |
| SCHEMBL2567840 | 0.64 | NR3C1 (0.52) | NR3C1NR3C2PGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049112-B1 | TREATING INFECTIONS AND SEQUELAE THEREOF WITH COMBINED DISSOCIATED GLUCOCORTICOID RECEPTOR AGONISTS AND ANTI-INFECTIVE AGENTS | BAUSCH & LOMB (US) | 2012-03-14 | — | — | EP | disclosed |