Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 13/20 | 0.42 |
| ▸ | PGR | P06401 | 12/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4037362 | 0.81 | NR3C1 (0.57) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3825739 | 0.81 | AAK1 (0.31) | NR3C1NR3C2 | |
| SCHEMBL3714466 | 0.78 | NR3C1 (0.65) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL10313415 | 0.76 | NR3C1 (0.69) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL292335 | 0.76 | NR3C1 (0.69) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3707341 | 0.76 | NR3C1 (0.61) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3653908 | 0.75 | NR3C1 (0.55) | NR3C1NR3C2PGR | |
| SCHEMBL450470 | 0.74 | NR3C1 (0.73) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3948579 | 0.73 | NR3C1 (0.61) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL5801771 | 0.72 | NR3C1 (0.47) | NR3C1NR3C2PGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190431-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST FOR TREATING OR CONTROLLING ANTERIOR-SEGMENT INFLAMMATION | Bausch & Lomb Incorporated (US) | 2010-06-02 | — | — | EP | disclosed |
| EP-2051710-A2 | COMPOSITIONS AND METHODS FOR TREATING, REDUCING, AMELIORATING, OR ALLEVIATING POSTERIOR-SEGMENT OPHTHALMIC DISEASES | Bausch & Lomb Incorporated (US) | 2009-04-29 | — | — | EP | disclosed |
| WO-2009023471-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST FOR TREATING OR CONTROLLING ANTERIOR-SEGMENT INFLAMMATION | BAUSCH & LOMB INCORPORATED (US) | 2009-02-19 | — | — | WO | disclosed |
| WO-2008021729-A2 | COMPOSITIONS AND METHODS FOR TREATING, REDUCING, AMELIORATING, OR ALLEVIATING POSTERIOR-SEGMENT OPHTHALMIC DISEASES | BAUSCH & LOMB INCORPORATED (US) | 2008-02-21 | — | — | WO | disclosed |