Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3828334 | 0.87 | ALDH1A1 (0.48) | ALDH1A1HPGDNPC1RAB9AMAPT | |
| SCHEMBL13494055 | 0.82 | NPC1 (0.47) | LCKALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL12034441 | 0.82 | CDC7 (0.44) | LCKALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL22750755 | 0.81 | LCK (0.41) | LCKALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL25406098 | 0.81 | NPC1 (0.45) | LCKALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL5528925 | 0.79 | CNR1 (0.46) | LCKALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL6985283 | 0.79 | ALDH1A1 (0.53) | LCKALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL27638360 | 0.79 | GRM6 (0.41) | LCKALDH1A1HPGDMAPT | |
| SCHEMBL10265322 | 0.77 | ALDH1A1 (0.40) | LCKALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL25296783 | 0.77 | L3MBTL1 (0.58) | LCKALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116891469-A | Thiazole derivative and preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-10-17 | — | — | CN | disclosed |