Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13650887 | 0.84 | TDP1 (0.40) | APLNRTDP1GAAMEN1KMT2A | |
| SCHEMBL27732646 | 0.82 | APLNR (0.54) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL14939227 | 0.82 | APLNR (0.50) | APLNRTDP1GAAMEN1KMT2A | |
| SCHEMBL18476417 | 0.81 | APLNR (0.56) | APLNRTDP1GAAMEN1KMT2A | |
| SCHEMBL23419356 | 0.81 | APLNR (0.49) | APLNRTDP1MEN1KMT2AMAPK1 | |
| SCHEMBL31143867 | 0.81 | TSHR (0.52) | APLNRTDP1GAAMEN1KMT2A | |
| SCHEMBL10535135 | 0.81 | APLNR (0.53) | APLNRTDP1GAAMEN1KMT2A | |
| SCHEMBL5832179 | 0.81 | APLNR (0.49) | APLNRTDP1GAAMEN1KMT2A | |
| SCHEMBL8893844 | 0.81 | APLNR (0.49) | APLNRTDP1GAAMEN1KMT2A | |
| SCHEMBL3458796 | 0.79 | APLNR (0.54) | APLNRTDP1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116891484-A | Condensed ring compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-10-17 | — | — | CN | disclosed |