Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.75 |
| ▸ | MAPT | P10636 | 9/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 7/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3546064 | 0.88 | LMNA (0.75) | ALDH1A1MAPK1L3MBTL1MAPTTDP1 | |
| SCHEMBL23486528 | 0.86 | ALDH1A1 (1.00) | ALDH1A1MAPK1L3MBTL1MAPTLMNA | |
| SCHEMBL3485682 | 0.84 | MAPK1 (1.00) | ALDH1A1MAPK1L3MBTL1MAPTTDP1 | |
| SCHEMBL2711990 | 0.83 | MAPT (0.77) | ALDH1A1MAPK1L3MBTL1MAPTTDP1 | |
| SCHEMBL7800482 | 0.83 | GAA (0.72) | ALDH1A1MAPK1L3MBTL1MAPTTDP1 | |
| SCHEMBL23536501 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MAPK1L3MBTL1MAPTTDP1 | |
| SCHEMBL29931934 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MAPK1L3MBTL1MAPTTDP1 | |
| SCHEMBL690222 | 0.82 | MAPT (0.63) | ALDH1A1MAPK1L3MBTL1MAPTTDP1 | |
| SCHEMBL259406 | 0.82 | MAPT (0.69) | ALDH1A1MAPK1L3MBTL1MAPTTDP1 | |
| SCHEMBL2712983 | 0.82 | MAPT (0.63) | ALDH1A1MAPK1L3MBTL1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116891484-A | Condensed ring compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-10-17 | — | — | CN | disclosed |