Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27672161 | 0.92 | KDM1A (0.39) | KDM1AALDH1A1LMNASMN1; SMN2PLK1 | |
| SCHEMBL41241 | 0.92 | KDM1A (0.39) | KDM1AALDH1A1LMNASMN1; SMN2PLK1 | |
| Phosphine SCHEMBL27662410 | 0.90 | KDM1A (0.38) | KDM1AALDH1A1LMNASMN1; SMN2PLK1 | |
| Glycine SCHEMBL2322797 | 0.87 | PDE4A (0.35) | KDM1AALDH1A1LMNASMN1; SMN2PLK1 | |
| SCHEMBL13723726 | 0.86 | KDM1A (0.39) | KDM1AALDH1A1LMNASMN1; SMN2PLK1 | |
| SCHEMBL15455784 | 0.83 | TDP1 (0.40) | ALDH1A1LMNASMN1; SMN2PLK1APOBEC3G | |
| SCHEMBL10616922 | 0.82 | MAPT (0.43) | ALDH1A1LMNASMN1; SMN2PLK1APOBEC3G | |
| SCHEMBL11581587 | 0.81 | HTT (0.44) | ALDH1A1PLK1APOBEC3GTDP1HPGD | |
| Thiouracil SCHEMBL28203909 | 0.81 | TP53 (0.54) | KDM1AALDH1A1LMNASMN1; SMN2PLK1 | |
| Imidazole SCHEMBL27283840 | 0.80 | TDP1 (0.39) | ALDH1A1PLK1APOBEC3GPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117363716-A | Detection reagent and kit for mutation sites of genes related to drug-induced granulocytopenia and liver injury and application of detection reagent and kit | 济南爱新卓尔医学检验有限公司 | 2024-01-09 | — | — | CN | disclosed |