Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MPO | P05164 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | TPO | P07202 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LPO | P22079 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27672161 | 0.88 | KDM1A (0.39) | KDM1AALDH1A1LPOLMNASMN1; SMN2 | |
| SCHEMBL41241 | 0.88 | KDM1A (0.39) | KDM1AALDH1A1LPOLMNASMN1; SMN2 | |
| Phosphine SCHEMBL27662410 | 0.86 | KDM1A (0.38) | KDM1AALDH1A1LPOLMNASMN1; SMN2 | |
| SCHEMBL13723726 | 0.82 | KDM1A (0.39) | KDM1AALDH1A1LMNASMN1; SMN2PLK1 | |
| Propylthiouracil SCHEMBL5493725 | 0.82 | LPO (0.61) | TP53ALDH1A1MPOTPOTSHR | |
| Thiourea SCHEMBL29139740 | 0.81 | KDM1A (0.35) | KDM1AALDH1A1LMNASMN1; SMN2PLK1 | |
| SCHEMBL10616922 | 0.79 | MAPT (0.43) | ALDH1A1LMNASMN1; SMN2PLK1APOBEC3G | |
| SCHEMBL11581587 | 0.77 | HTT (0.44) | TP53ALDH1A1TSHRPLK1APOBEC3G | |
| Glycine SCHEMBL2322797 | 0.77 | PDE4A (0.35) | KDM1AALDH1A1LMNASMN1; SMN2PLK1 | |
| Imidazole SCHEMBL27283840 | 0.76 | TDP1 (0.39) | ALDH1A1PLK1APOBEC3GADORA3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114522193-A | Mongolian medicine composition for treating thyromegaly, preparation method and quality control method | 锡林其其格 | 2022-05-24 | — | — | CN | disclosed |
| CN-105116027-B | Propylthiouracil (PTU) concentration analysis device and method based on surface acoustic wave series resonator biology tongue | 浙江工商大学 | 2018-03-09 | — | — | CN | disclosed |