Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31301103 | 0.83 | NPC1 (0.53) | SMN1; SMN2NPC1RAB9ACES1CYP1A2 | |
| SCHEMBL1200124 | 0.83 | NPC1 (0.53) | SMN1; SMN2NPC1RAB9ACES1CYP1A2 | |
| SCHEMBL4771351 | 0.78 | CYP1A2 (0.35) | SMN1; SMN2NPC1RAB9ACES1GAA | |
| SCHEMBL13114103 | 0.77 | NPC1 (0.39) | SMN1; SMN2HTTNPC1RAB9ACES1 | |
| SCHEMBL19435728 | 0.74 | NPC1 (0.50) | SMN1; SMN2NPC1RAB9ACYP1A2MEN1 | |
| SCHEMBL8111658 | 0.74 | NOTUM (0.45) | SMN1; SMN2HTTNOTUMNPC1RAB9A | |
| SCHEMBL9501828 | 0.73 | MTNR1A (0.42) | SMN1; SMN2HTTNOTUMNPC1RAB9A | |
| SCHEMBL12843388 | 0.73 | CES1 (0.39) | SMN1; SMN2HTTNPC1RAB9ACES1 | |
| SCHEMBL19775784 | 0.72 | CES1 (0.39) | SMN1; SMN2HTTNPC1RAB9ACES1 | |
| SCHEMBL27281859 | 0.71 | CYP1A2 (0.45) | NPC1RAB9AGAACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110831926-B | Tetrahydronaphtyl urea derivatives | 持田制药株式会社 | 2023-11-21 | — | — | CN | disclosed |