Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 19/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19699379 | 0.81 | NR1H4 (0.48) | NR1H4 | |
| SCHEMBL19689515 | 0.78 | NR1H4 (0.51) | NR1H4 | |
| SCHEMBL30775168 | 0.78 | NR1H4 (0.51) | NR1H4 | |
| SCHEMBL22320341 | 0.77 | CA12 (0.39) | NR1H4CA12CA1CA9HSD17B13 | |
| SCHEMBL19690343 | 0.76 | NR1H4 (0.44) | NR1H4 | |
| SCHEMBL29216000 | 0.75 | NR1H4 (0.54) | NR1H4HSD17B13 | |
| SCHEMBL30775154 | 0.75 | NR1H4 (0.54) | NR1H4HSD17B13 | |
| SCHEMBL29139862 | 0.73 | NR1H4 (0.77) | NR1H4HSD17B13 | |
| SCHEMBL29736070 | 0.72 | MET (0.37) | CA12CA1CA9 | |
| SCHEMBL19689482 | 0.72 | MET (0.37) | CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924266-A | Compounds that modulate FXR (NR 1H 4) | 吉利德科学公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117924267-A | Compounds that modulate FXR (NR 1H 4) | 吉利德科学公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-109476636-B | Compounds that modulate FXR (NR 1H 4) | 吉利德科学公司 | 2024-01-09 | — | — | CN | disclosed |