Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1700360 | 0.84 | LMNA (0.45) | MAPTLMNAKDM4EALDH1A1POLB | |
| SCHEMBL1700226 | 0.77 | LMNA (0.48) | MAPTLMNAMAPK1KDM4EALDH1A1 | |
| SCHEMBL30467963 | 0.77 | LMNA (0.48) | MAPTLMNAMAPK1KDM4EALDH1A1 | |
| SCHEMBL30467942 | 0.76 | BCL2 (0.43) | MAPTLMNAALDH1A1POLBATM | |
| SCHEMBL1702077 | 0.76 | BCL2 (0.43) | MAPTLMNAALDH1A1POLBATM | |
| SCHEMBL21331172 | 0.76 | CYP1A2 (0.48) | CYP2D6CYP2C19CYP1A2SMN1; SMN2RAB9A | |
| SCHEMBL1701837 | 0.74 | MAPT (0.41) | MAPTLMNAGAAKDM4EALDH1A1 | |
| SCHEMBL23944123 | 0.73 | HRH3 (0.32) | RAB9ANPC1MAPTMAPK1GAA | |
| SCHEMBL13518365 | 0.71 | HTT (0.45) | CYP2D6CYP2C19CYP1A2SMN1; SMN2RAB9A | |
| SCHEMBL21331188 | 0.70 | SSTR4 (0.38) | CYP2D6CYP2C19CYP1A2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112437772-B | Bcl-2 inhibitors | 百济神州有限公司 | 2023-11-21 | — | — | CN | disclosed |