Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | TLR4 | O00206 | 1/20 | 0.51 |
| ▸ | CPB1 | P15086 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 5/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18560208 | 0.85 | ALDH1A1 (0.56) | ALDH1A1GAATSHREPHX1TLR4 | |
| SCHEMBL8606778 | 0.84 | ALDH1A1 (0.61) | ALDH1A1GAATSHREPHX1TLR4 | |
| SCHEMBL10586925 | 0.84 | ALDH1A1 (0.61) | ALDH1A1GAATSHREPHX1TLR4 | |
| SCHEMBL3549759 | 0.81 | ALDH1A1 (0.61) | ALDH1A1GAATSHREPHX1TLR4 | |
| SCHEMBL381922 | 0.81 | ALDH1A1 (0.85) | ALDH1A1GAATSHREPHX1TLR4 | |
| SCHEMBL3948461 | 0.81 | ALDH1A1 (0.85) | ALDH1A1GAATSHREPHX1TLR4 | |
| SCHEMBL3948456 | 0.81 | ALDH1A1 (0.85) | ALDH1A1GAATSHREPHX1TLR4 | |
| SCHEMBL18623681 | 0.81 | ALDH1A1 (0.67) | ALDH1A1GAATSHREPHX1TLR4 | |
| SCHEMBL3538525 | 0.81 | ALDH1A1 (0.67) | ALDH1A1GAATSHREPHX1TLR4 | |
| SCHEMBL14709053 | 0.81 | ALDH1A1 (0.60) | ALDH1A1GAATSHREPHX1TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4549438-A1 | FIVE-MEMBERED AND SIX-MEMBERED NITROGEN-CONTAINING COMPOUND, AND INTERMEDIATE, PREPARATION METHOD AND USE THEREOF | Hangzhou Synrx Therapeutics Biomedical Technology Co., Ltd. (CN) | 2025-05-07 | — | — | EP | disclosed |
| CN-117304183-A | Five-membered and six-membered nitrogen-containing compound, intermediate thereof, preparation method and application | 杭州圣域生物医药科技有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-117098753-A | Modulators of integrated stress response pathways | 埃沃特克国际有限责任公司 | 2023-11-21 | — | — | CN | disclosed |
| EP-4232153-A1 | MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY | Evotec International GmbH (DE) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022084446-A1 | MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY | EVOTEC INTERNATIONAL GMBH (DE) | 2022-04-28 | — | — | WO | disclosed |