Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 6/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | TEK | Q02763 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29141649 | 0.80 | BRD4 (0.62) | SMN1; SMN2MAPTLCKBRD4TSHR | |
| SCHEMBL29141645 | 0.77 | SMN1; SMN2 (0.63) | SMN1; SMN2MAPTLCKBRD4TSHR | |
| SCHEMBL29141652 | 0.76 | SMN1; SMN2 (0.60) | SMN1; SMN2MAPTLCKBRD4TSHR | |
| SCHEMBL29141659 | 0.75 | LCK (0.58) | SMN1; SMN2MAPTLCKBRD4TSHR | |
| SCHEMBL4921707 | 0.72 | SMN1; SMN2 (0.74) | SMN1; SMN2MAPTLCKBRD4TSHR | |
| SCHEMBL29501954 | 0.72 | LMNA (0.60) | SMN1; SMN2MAPTBRD4TSHRHTT | |
| SCHEMBL4921135 | 0.72 | HSD17B10 (0.74) | SMN1; SMN2MAPTLCKBRD4TSHR | |
| SCHEMBL4913787 | 0.70 | RAB9A (0.72) | SMN1; SMN2MAPTLCKBRD4TSHR | |
| SCHEMBL29141661 | 0.70 | HTT (0.45) | SMN1; SMN2MAPTLCKTSHRHTT | |
| SCHEMBL4920143 | 0.70 | SMN1; SMN2 (0.87) | SMN1; SMN2MAPTLCKBRD4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430609-B | Purine derivative compound, preparation method and application thereof | 东北农业大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-117430609-A | Purine derivative compound, preparation method and application thereof | 东北农业大学 | 2024-01-23 | — | — | CN | disclosed |