Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23290037 | 0.86 | HTR2C (0.35) | KDM4EMAPTMAPK1L3MBTL1HTR2A | |
| SCHEMBL8610877 | 0.77 | MEN1 (0.35) | KDM4EHTR2AHTR2CALDH1A1GAA | |
| SCHEMBL29142064 | 0.72 | HTR2C (0.35) | HTR2AHTR2CCYP11B1CYP11B2KCNH2 | |
| SCHEMBL18323591 | 0.67 | HCAR3 (0.58) | MAPTALDH1A1 | |
| SCHEMBL24824382 | 0.67 | HTR2A (0.65) | KDM4EMAPTMAPK1L3MBTL1HTR2A | |
| SCHEMBL8615623 | 0.66 | ATM (0.34) | KDM4EHTR2AHTR2CALDH1A1CYP11B1 | |
| SCHEMBL17232744 | 0.66 | ADORA2A (0.62) | KDM4EMAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL29142030 | 0.65 | RBP4 (0.32) | — | |
| SCHEMBL15832959 | 0.64 | KDM4E (0.41) | KDM4EMAPTMAPK1L3MBTL1HTR2A | |
| SCHEMBL21334032 | 0.64 | KDM4E (0.41) | KDM4EMAPTMAPK1L3MBTL1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117440774-A | Biomarkers of age-related macular degeneration | 倍亮生物有限责任公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-114364382-A | Formulations and methods of use of RBP4 inhibitors | 倍亮生物有限责任公司 | 2022-04-15 | — | — | CN | disclosed |