SCHEMBL2914384

SCHEMBL2914384

OCCCc1ccc(O)c(-c2ccccc2)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 4/20 0.70
IGF1R P08069 3/20 0.53
ALOX15 P16050 3/20 0.53
CNR1 P21554 1/20 0.47
CNR2 P34972 1/20 0.47
ALOX5 P09917 3/20 0.46
ALDH1A1 P00352 2/20 0.46
KDM4E B2RXH2 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
HPGD P15428 1/20 0.45
BCL2L1 Q07817 1/20 0.45
HSD17B10 Q99714 1/20 0.45
LTA4H P09960 1/20 0.44
EPHX2 P34913 1/20 0.44
BCHE P06276 1/20 0.43
PELI1 Q96FA3 1/20 0.42
PSMB5 P28074 1/20 0.42
ACMSD Q8TDX5 1/20 0.42
HSD17B1 P14061 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8956674 0.93 BACE1 (0.74) BACE1IGF1RALOX15CNR1CNR2
SCHEMBL8956703 0.93 BACE1 (0.74) BACE1IGF1RALOX15CNR1CNR2
SCHEMBL8956585 0.91 BACE1 (0.72) BACE1IGF1RALOX15CNR1CNR2
SCHEMBL10699069 0.91 BACE1 (0.72) BACE1IGF1RALOX15CNR1CNR2
SCHEMBL28277965 0.91 BACE1 (0.72) BACE1IGF1RALOX15CNR1CNR2
SCHEMBL10535059 0.90 BACE1 (0.57) BACE1IGF1RALOX15CNR1CNR2
SCHEMBL15224151 0.89 BACE1 (0.74) BACE1IGF1RALOX15CNR1CNR2
SCHEMBL8956610 0.89 BACE1 (0.79) BACE1IGF1RALOX15CNR1CNR2
SCHEMBL4591101 0.86 BACE1 (0.66) BACE1IGF1RALOX15CNR1CNR2
SCHEMBL27641734 0.86 BACE1 (0.66) BACE1IGF1RALOX15CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2110370-B1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2010-09-01 EP disclosed
EP-1348686-B1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2010-03-03 EP disclosed
EP-2110370-A1 Method of producing p-hydroxyphenylalkanols Sumitomo Chemical Company, Limited (JP) 2009-10-21 EP disclosed
CN-1307139-C Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2007-03-28 CN disclosed
US-6717020-B2 HIGH YIELD REACTION OF PHENOLS AND UNSATURATED ALCOHOLS IN PRESENCE OF SUCH AS TITANIUM TETRAETHOXIDE AND SODIUM METHOXIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-04-06 US disclosed
US-20030195379-A1 Method of producing p-Hydroxyphenylalkanols SUMITOMO CHEMICAL COMPANY, LIMITED 2003-10-16 US disclosed
CN-1448379-A Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2003-10-15 CN disclosed
EP-1348686-A1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-10-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030195379-A1 Method of producing p-Hydroxyphenylalkanols ADH1C, NR1H3, ADH5 BACE1 4580/4885IGF1R 3333/4885ALOX15 892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.