Ether

Ether

SCHEMBL29144591

CCOCC.COC(=O)C(CC1CC1)NC(=O)OCc1ccccc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CTSK P43235 7/20 0.54
CTSB P07858 3/20 0.54
CTSL P07711 2/20 0.54
CTSS P25774 2/20 0.54
KYNU Q16719 1/20 0.53
ALDH1A1 P00352 3/20 0.51
ALOX15 P16050 1/20 0.51
TSHR P16473 4/20 0.48
CYP3A4 P08684 3/20 0.48
CASP1 P29466 1/20 0.48
MEN1 O00255 1/20 0.47
MAPT P10636 1/20 0.47
KMT2A Q03164 1/20 0.47
SIRT2 Q8IXJ6 1/20 0.47
SIRT1 Q96EB6 1/20 0.47
SIRT3 Q9NTG7 1/20 0.47
IDO1 P14902 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7469120 0.94 CTSK (0.59) CTSKCTSBCTSLCTSSKYNU
SCHEMBL30764688 0.94 CTSK (0.59) CTSKCTSBCTSLCTSSKYNU
SCHEMBL24103095 0.89 CTSK (0.57) CTSKCTSBCTSLCTSSCASP1
SCHEMBL18822633 0.86 ITGB3 (0.57) CTSKCTSBCTSLCTSSKYNU
SCHEMBL18803800 0.86 ITGB3 (0.57) CTSKCTSBCTSLCTSSKYNU
SCHEMBL6505256 0.86 SMN1; SMN2 (0.52) CTSKCTSBCTSLCTSSKYNU
Hydrochloric Acid SCHEMBL28593461 0.85 ITGB3 (0.56) CTSKCTSBCTSLCTSSKYNU
SCHEMBL3008067 0.85 CTSK (0.53) CTSKCTSBCTSLCTSSKYNU
Hydrochloric Acid SCHEMBL18788051 0.85 ITGB3 (0.56) CTSKCTSBCTSLCTSSKYNU
SCHEMBL15649130 0.85 CTSK (0.60) CTSKCTSBCTSLCTSSCASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117136178-A SARS-COV-2 Mpro inhibitor compounds 赫帕雷斯治疗有限公司 2023-11-28 CN disclosed