SCHEMBL29145174

SCHEMBL29145174

CCc1cccc(-c2nc3ccccc3n2C(=O)OC)c1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.50
ASAH1 Q13510 2/20 0.47
CNR2 P34972 2/20 0.46
TP53 P04637 2/20 0.45
HDAC1 Q13547 6/20 0.44
HDAC8 Q9BY41 6/20 0.44
HDAC6 Q9UBN7 6/20 0.44
MAPT P10636 2/20 0.44
CNR1 P21554 1/20 0.43
LMNA P02545 1/20 0.43
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43
DRD2 P14416 1/20 0.43
TBXA2R P21731 1/20 0.43
PSMD14 O00487 1/20 0.42
GAA P10253 1/20 0.42
KDR P35968 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29145123 0.89 L3MBTL1 (0.46) L3MBTL1ASAH1CNR2TP53HDAC1
SCHEMBL29145103 0.86 CNR2 (0.54) L3MBTL1ASAH1CNR2TP53MAPT
SCHEMBL29145171 0.86 L3MBTL1 (0.56) L3MBTL1ASAH1CNR2TP53HDAC1
SCHEMBL29145179 0.85 KDR (0.50) L3MBTL1ASAH1CNR2TP53HDAC1
SCHEMBL29145160 0.83 L3MBTL1 (0.61) L3MBTL1CNR2MAPTCNR1LMNA
SCHEMBL29145125 0.83 L3MBTL1 (0.52) L3MBTL1CNR2HDAC1HDAC8HDAC6
SCHEMBL29145163 0.80 CNR2 (0.52) L3MBTL1ASAH1CNR2TP53CNR1
SCHEMBL29145083 0.78 CNR2 (0.59) L3MBTL1ASAH1CNR2TP53CNR1
SCHEMBL29145085 0.78 CNR2 (0.50) L3MBTL1ASAH1CNR2CNR1LMNA
SCHEMBL29145108 0.78 L3MBTL1 (0.54) L3MBTL1ASAH1CNR2LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430738-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN claimed
CN-117430737-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN claimed
CN-117430738-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN disclosed
CN-117430737-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN disclosed