SCHEMBL29145103

SCHEMBL29145103

CCc1ccc(-c2nc3ccccc3n2C(=O)OC)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 3/20 0.54
L3MBTL1 Q9Y468 3/20 0.53
DRD2 P14416 1/20 0.53
TBXA2R P21731 1/20 0.53
CNR1 P21554 1/20 0.48
KDM4E B2RXH2 5/20 0.47
ALDH1A1 P00352 4/20 0.47
LMNA P02545 4/20 0.47
HTT P42858 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
GAA P10253 2/20 0.44
PSMD14 O00487 1/20 0.44
NPSR1 Q6W5P4 3/20 0.44
TSHR P16473 1/20 0.44
TP53 P04637 2/20 0.44
ASAH1 Q13510 1/20 0.44
MAPT P10636 2/20 0.43
HPGD P15428 2/20 0.43
RECQL P46063 1/20 0.43
HSD17B10 Q99714 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29145163 0.90 CNR2 (0.52) CNR2L3MBTL1DRD2TBXA2RCNR1
SCHEMBL29145085 0.88 CNR2 (0.50) CNR2L3MBTL1DRD2TBXA2RCNR1
SCHEMBL29145083 0.87 CNR2 (0.59) CNR2L3MBTL1DRD2TBXA2RCNR1
SCHEMBL29145174 0.86 L3MBTL1 (0.50) CNR2L3MBTL1DRD2TBXA2RCNR1
SCHEMBL29145160 0.86 L3MBTL1 (0.61) CNR2L3MBTL1DRD2TBXA2RCNR1
SCHEMBL14825918 0.84 CNR2 (0.56) CNR2L3MBTL1DRD2TBXA2RCNR1
SCHEMBL29145164 0.84 DRD2 (0.58) CNR2L3MBTL1DRD2TBXA2RCNR1
SCHEMBL29145131 0.84 CNR2 (0.50) CNR2L3MBTL1DRD2TBXA2RCNR1
SCHEMBL21705334 0.82 CNR2 (0.54) CNR2L3MBTL1DRD2TBXA2RCNR1
SCHEMBL29145108 0.81 L3MBTL1 (0.54) CNR2L3MBTL1KDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430738-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN claimed
CN-117430737-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN claimed
CN-117430738-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN disclosed
CN-117430737-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN disclosed