SCHEMBL29145192

SCHEMBL29145192

Cc1cccc(-c2nc3ccccc3n2C(N)=O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.52
KMT2A Q03164 2/20 0.50
ASAH1 Q13510 1/20 0.50
KDR P35968 3/20 0.49
MAPT P10636 2/20 0.48
TLR8 Q9NR97 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
KDM4E B2RXH2 2/20 0.47
NPC1 O15118 1/20 0.47
PKM P14618 1/20 0.47
RAB9A P51151 1/20 0.47
CNR2 P34972 2/20 0.46
PDGFRB P09619 1/20 0.46
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
CNR1 P21554 1/20 0.44
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6890976 0.86 KDM4E (0.56) KMT2ASMN1; SMN2KDM4ENPC1PKM
SCHEMBL29145098 0.86 KDM4E (0.52) TP53KMT2ASMN1; SMN2KDM4ENPC1
SCHEMBL29145179 0.85 KDR (0.50) TP53KMT2AASAH1KDRMAPT
SCHEMBL29145105 0.85 KDM4E (0.56) TP53KMT2AASAH1KDRSMN1; SMN2
SCHEMBL29145175 0.83 ASAH1 (0.47) TP53KMT2AASAH1KDRMAPT
SCHEMBL29145171 0.83 L3MBTL1 (0.56) TP53KMT2AASAH1MAPTSMN1; SMN2
SCHEMBL26052332 0.80 TP53 (0.48) TP53KMT2AASAH1MAPTCNR2
SCHEMBL28646061 0.79 ESR1 (0.52) TP53KMT2ASMN1; SMN2KDM4ENPC1
SCHEMBL6356326 0.79 CNR2 (0.52) TP53KMT2ASMN1; SMN2KDM4ENPC1
SCHEMBL29145129 0.78 KMT2A (0.61) TP53KMT2AMAPTKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430738-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN claimed
CN-117430737-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN claimed
CN-117430738-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN disclosed
CN-117430737-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN disclosed