Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | NPR3 | P17342 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24514176 | 1.00 | ADRB2 (0.47) | ADRB2ADRB1ADRB3SLC7A5KMT2A | |
| SCHEMBL29145376 | 0.91 | LNPEP (0.46) | SLC7A5LNPEPERAP2ROCK2SMN1; SMN2 | |
| SCHEMBL24514069 | 0.91 | LNPEP (0.46) | SLC7A5LNPEPERAP2ROCK2SMN1; SMN2 | |
| SCHEMBL2995178 | 0.90 | SLC7A5 (0.56) | SLC7A5LNPEPROCK2NPR3STAT3 | |
| SCHEMBL2995175 | 0.90 | SLC7A5 (0.56) | SLC7A5LNPEPROCK2NPR3STAT3 | |
| Hydrochloric Acid SCHEMBL23466585 | 0.89 | SLC7A5 (0.55) | SLC7A5KMT2AMEN1LNPEPROCK2 | |
| SCHEMBL24514067 | 0.89 | SLC7A5 (0.44) | SLC7A5LNPEPERAP2ROCK2STAT3 | |
| SCHEMBL23486555 | 0.89 | SLC7A5 (0.49) | SLC7A5LNPEPROCK2HDAC8 | |
| SCHEMBL29139603 | 0.87 | MEN1 (0.49) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL23486798 | 0.87 | MEN1 (0.49) | ADRB2ADRB1ADRB3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117480164-B | Factor XIa inhibitor and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-117480164-A | Factor XIa inhibitor and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-01-30 | — | — | CN | disclosed |