Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | HCK | P08631 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29145773 | 1.00 | KDM5A (0.39) | KDM5ABTKKMT2AMEN1KDM4E | |
| SCHEMBL24711137 | 0.83 | ALDH1A1 (0.43) | KMT2AMEN1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL24710874 | 0.83 | ALDH1A1 (0.43) | KMT2AMEN1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL29145754 | 0.80 | KDM6B (0.36) | BTKKMT2AKDM4EEGFRKDM6B | |
| SCHEMBL29145770 | 0.80 | KDM6B (0.36) | BTKKMT2AKDM4EEGFRKDM6B | |
| SCHEMBL30277875 | 0.76 | CYP1A2 (0.49) | MAPT | |
| SCHEMBL24710904 | 0.76 | CYP1A2 (0.49) | MAPT | |
| SCHEMBL29145749 | 0.72 | KMT2A (0.38) | BTKKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL29145747 | 0.72 | KMT2A (0.38) | BTKKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL26621136 | 0.71 | BTK (0.40) | BTKHSD17B10HPGDEGFRJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117480162-A | Compounds for the treatment or prophylaxis of PRMT5 mediated diseases | 阿古诺治疗有限公司 | 2024-01-30 | — | — | CN | disclosed |