Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 3/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.36 |
| ▸ | KDM5C | P41229 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29145770 | 1.00 | KDM6B (0.36) | KDM6BKDM2AKDM5CKDM4CKDM3A | |
| SCHEMBL29145750 | 0.85 | HSD11B1 (0.36) | KDM6BKDM2AKDM5CKDM4CKDM3A | |
| SCHEMBL24710458 | 0.83 | FPR2 (0.45) | RECQLBTKKMT2AKDM4E | |
| SCHEMBL24710473 | 0.83 | FPR2 (0.45) | RECQLBTKKMT2AKDM4E | |
| SCHEMBL29145773 | 0.80 | KDM5A (0.39) | KDM6BKDM2AKDM5CKDM4CKDM3A | |
| SCHEMBL29145776 | 0.80 | KDM5A (0.39) | KDM6BKDM2AKDM5CKDM4CKDM3A | |
| SCHEMBL24710862 | 0.77 | CYP1A2 (0.50) | SMN1; SMN2 | |
| SCHEMBL24711134 | 0.77 | CYP1A2 (0.50) | SMN1; SMN2 | |
| SCHEMBL26621136 | 0.74 | BTK (0.40) | HSD11B1BTKEGFR | |
| SCHEMBL29145743 | 0.72 | KDM2A (0.36) | KDM6BKDM2AKDM5CKDM4CKDM3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117480162-A | Compounds for the treatment or prophylaxis of PRMT5 mediated diseases | 阿古诺治疗有限公司 | 2024-01-30 | — | — | CN | disclosed |