SCHEMBL291460

SCHEMBL291460

OC1CCc2ccccc2C1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.57
PLAU P00749 1/20 0.56
CYP1A2 P05177 1/20 0.47
CYP11B1 P15538 1/20 0.47
CYP11B2 P19099 1/20 0.47
MTNR1A P48039 3/20 0.47
MTNR1B P49286 3/20 0.47
HTR1A P08908 1/20 0.47
GRIN2B Q13224 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
TSHR P16473 1/20 0.42
CYP19A1 P11511 1/20 0.42
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13998125 1.00 ANPEP (0.57) ANPEPPLAUCYP1A2CYP11B1CYP11B2
SCHEMBL6951241 1.00 ANPEP (0.57) ANPEPPLAUCYP1A2CYP11B1CYP11B2
SCHEMBL2943529 1.00 ANPEP (0.57) ANPEPPLAUCYP1A2CYP11B1CYP11B2
Ammonia Solution, Strong SCHEMBL6107709 0.98 ANPEP (0.55) ANPEPPLAUCYP1A2CYP11B1CYP11B2
Water SCHEMBL22090286 0.98 ANPEP (0.55) ANPEPPLAUCYP1A2CYP11B1CYP11B2
Iodide SCHEMBL10818108 0.96 ANPEP (0.53) ANPEPPLAUCYP1A2CYP11B1CYP11B2
Sulfurous Acid SCHEMBL10813687 0.88 ANPEP (0.47) ANPEPPLAUCYP1A2CYP11B1CYP11B2
SCHEMBL885265 0.87 ANPEP (0.52) ANPEPPLAUMTNR1AMTNR1BHTR1A
SCHEMBL13482664 0.86 TSHR (0.50) ANPEPPLAUCYP1A2CYP11B1CYP11B2
Vinyl Ether SCHEMBL27610276 0.85 ANPEP (0.45) ANPEPPLAUCYP1A2CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 825 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111393258-B Method for synthesizing tetrahydronaphthalene-2-alcohol derivative compound 浙江工业大学 2022-08-23 CN claimed
EP-3883932-A1 INHIBITORS OF GLI1 AS THERAPEUTIC AGENTS New York University (US) 2021-09-29 EP claimed
CN-111393258-A Method for synthesizing tetrahydronaphthalene-2-alcohol derivative compound 浙江工业大学 2020-07-10 CN claimed
US-20200197377-A1 METHODS FOR IMPROVING MEMORY AND COGNITION AND FOR TREATING MEMORY AND COGNITIVE DISORDERS CAVION, INC. (US) 2020-06-25 US claimed
US-20200163943-A1 METHODS FOR TREATING DRAVET SYNDROME CAVION, INC. (US) 2020-05-28 US claimed
EP-3615010-A1 METHODS FOR TREATING DRAVET SYNDROME Cavion, Inc. (US) 2020-03-04 EP claimed
EP-3615521-A1 METHODS FOR IMPROVING MEMORY AND COGNITION AND FOR TREATING MEMORY AND COGNITIVE DISORDERS Cavion, Inc. (US) 2020-03-04 EP claimed
CN-110628475-A Process for pretreating rich gas in refinery and process for desulfurizing dry gas and/or liquefied gas 中国石油化工股份有限公司 2019-12-31 CN claimed
WO-2018200850-A1 METHODS FOR IMPROVING MEMORY AND COGNITION AND FOR TREATING MEMORY AND COGNITIVE DISORDERS CAVION, INC. (US) 2018-11-01 WO claimed
WO-2018200844-A1 METHODS FOR TREATING DRAVET SYNDROME CAVION, INC. (US) 2018-11-01 WO claimed
US-5427710-A Containing conjugated terpene, benzyl alcohol or derivative, organoclay rheological additive, optionally surfactant, additional terpene; biodegradable, nonflammable STEVENS EDWIN (US) 1995-06-27 US claimed
US-5425893-A Remover consists of conjugated terpene and terpene compounds, benzyl alcohol, surfactants, chlorophyll and organoclay thixotropic agents; nontoxic, and biodegradable STEVENS EDWIN (US) 1995-06-20 US claimed
WO-1995015322-A1 PROCESS FOR THE PREPARATION OF SUBSTITUTED 4-HYDROXYCOUMARINS GREAT LAKES FINE CHEMICALS LIMITED (GB) 1995-06-08 WO claimed
EP-0648201-A1 Enantioselective hydrogenation of the carbonyl bond using ruthenium complexes with biphosphine ligands. ELF AQUITAINE (FR) 1995-04-19 EP claimed
WO-1994024216-A1 PAINT STRIPPING COMPOSITIONS AND METHODS STEVENS EDWIN (US) 1994-10-27 WO claimed
WO-1994001390-A1 ENANTIOSELECTIVE CARBONYL GROUP HYDROGENATION METHOD USING RUTHENIUM/DIPHOSPHINE LIGAND COMPLEXES ELF AQUITAINE (FR) 1994-01-20 WO claimed
EP-0338311-B1 Oil composition containing hydrogenated oil NIPPON OIL CO LTD (JP) 1993-12-15 EP claimed
EP-0469683-A1 Derivatives of 4-amino-1-methyltetralins, their preparation and their application in therapy LABORATOIRES LUCIEN, Société Anonyme : (FR) 1992-02-05 EP claimed
US-4473711-A CHROMIUM(III) ION EXCHANGED RESIN CATALYST UNION CARBIDE CORPORATION (US) 1984-09-25 US claimed
EP-0098629-A1 Anti-coagulants of the 4-hydroxycoumarin type, the preparation thereof, and rodenticidal compositions (baits) comprising such anti-coagulants SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1984-01-18 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200163943-A1 METHODS FOR TREATING DRAVET SYNDROME CACNA1G, CACNB2, CACNA1H ANPEP 1649/4885PLAU 1521/4885CYP1A2 4235/4885
US-20200197377-A1 METHODS FOR IMPROVING MEMORY AND COGNITION AND FOR TREATING MEMORY AND COGNITIVE DISORDERS CACNA1G, CACNA1I, CACNA1H ANPEP 3130/4885PLAU 3126/4885CYP1A2 4356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.