Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.57 |
| ▸ | PLAU | P00749 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13998125 | 1.00 | ANPEP (0.57) | ANPEPPLAUCYP1A2CYP11B1CYP11B2 | |
| SCHEMBL291460 | 1.00 | ANPEP (0.57) | ANPEPPLAUCYP1A2CYP11B1CYP11B2 | |
| SCHEMBL6951241 | 1.00 | ANPEP (0.57) | ANPEPPLAUCYP1A2CYP11B1CYP11B2 | |
| Ammonia Solution, Strong SCHEMBL6107709 | 0.98 | ANPEP (0.55) | ANPEPPLAUCYP1A2CYP11B1CYP11B2 | |
| Water SCHEMBL22090286 | 0.98 | ANPEP (0.55) | ANPEPPLAUCYP1A2CYP11B1CYP11B2 | |
| Iodide SCHEMBL10818108 | 0.96 | ANPEP (0.53) | ANPEPPLAUCYP1A2CYP11B1CYP11B2 | |
| Sulfurous Acid SCHEMBL10813687 | 0.88 | ANPEP (0.47) | ANPEPPLAUCYP1A2CYP11B1CYP11B2 | |
| SCHEMBL885265 | 0.87 | ANPEP (0.52) | ANPEPPLAUMTNR1AMTNR1BHTR1A | |
| SCHEMBL13482664 | 0.86 | TSHR (0.50) | ANPEPPLAUCYP1A2CYP11B1CYP11B2 | |
| Vinyl Ether SCHEMBL27610276 | 0.85 | ANPEP (0.45) | ANPEPPLAUCYP1A2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200383951-A1 | METHODS FOR TREATING DEPENDENCE | BIOTIE THERAPIES INC (US) | 2020-12-10 | — | — | US | disclosed |
| EP-3617195-A1 | NOVEL TETRAHYDRONAPHTHYL UREA DERIVATIVES | Mochida Pharmaceutical Co., Ltd. (JP) | 2020-03-04 | — | — | EP | disclosed |
| US-10561638-B2 | Methods for treating dependence | BIOTIE THERAPIES, INC. (US) | 2020-02-18 | — | — | US | disclosed |
| EP-3251670-A1 | METHODS FOR TREATING DEPENDENCE | Biotie Therapies, Inc. (US) | 2017-12-06 | — | — | EP | disclosed |
| EP-2182804-B1 | METHODS FOR TREATING DEPENDENCE | BIOTIE THERAPIES INC (US) | 2017-05-24 | — | — | EP | disclosed |
| US-9320271-B2 | Microbial composition | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-04-26 | — | — | US | disclosed |
| US-20140356230-A1 | MICROBIAL COMPOSITION | ROHM AND HAAS COMPANY (US) | 2014-12-04 | — | — | US | disclosed |
| US-20140099336-A1 | Methods for Treating Dependence | BIOTIE THERAPIES, INC. (US) | 2014-04-10 | — | — | US | disclosed |
| WO-2012171114-A1 | SYNTHETIC EPIGALLOCATECHIN GALLATE (EGCG) ANALOGS | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2012-12-20 | — | — | WO | disclosed |
| CN-101951912-A | Treatment of post-traumatic stress disorder | SYNOSIA THERAPEUTICS | 2011-01-19 | — | — | CN | disclosed |
| CN-101815438-A | Method of treating dependency | SYNOSIA THERAPEUTICS INC | 2010-08-25 | — | — | CN | disclosed |
| US-7750135-B2 | Molecular design of thermostable alcohol dehydrogenase for synthesis for chiral aromatic alcohols | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2010-07-06 | — | — | US | disclosed |
| US-7750135-B2 | Molecular design of thermostable alcohol dehydrogenase for synthesis for chiral aromatic alcohols | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2010-07-06 | — | — | US | disclosed |
| US-7750135-B2 | Molecular design of thermostable alcohol dehydrogenase for synthesis for chiral aromatic alcohols | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2010-07-06 | — | — | US | disclosed |
| US-20090054403-A1 | Treatment of Post-Traumatic Stress Disorder | SYNOSIA THERAPEUTICS (US) | 2009-02-26 | — | — | US | disclosed |
| US-20090041800-A1 | Methods for Treating Dependence | SYNOSIA THERAPEUTICS, INC. (US) | 2009-02-12 | — | — | US | disclosed |
| US-20080220487-A1 | Molecular design of thermostable alcohol dehydrogenase for synthesis for chiral aromatic alcohols | THE BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2008-09-11 | — | — | US | disclosed |
| US-20080220487-A1 | Molecular design of thermostable alcohol dehydrogenase for synthesis for chiral aromatic alcohols | THE BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2008-09-11 | — | — | US | disclosed |
| US-20080220487-A1 | Molecular design of thermostable alcohol dehydrogenase for synthesis for chiral aromatic alcohols | THE BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2008-09-11 | — | — | US | disclosed |
| WO-2008013949-A2 | MOLECULAR DESIGN OF THERMOSTABLE ALCOHOL DEHYDROGENASE FOR SYNTHESIS FOR CHIRAL AROMATIC ALCOHOLS | MICHIGAN STATE UNIVERSITY (US) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080220487-A1 | Molecular design of thermostable alcohol dehydrogenase for synthesis for chiral aromatic alcohols | ADH5, ADH1C, ADH1A | ANPEP 481/4885PLAU 4474/4885CYP1A2 51/4885 |
| US-20140356230-A1 | MICROBIAL COMPOSITION | CD14, COMT, DRD4 | ANPEP 4013/4885PLAU 4848/4885CYP1A2 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.