Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | STAT6 | P42226 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | PYGL | P06737 | 9/20 | 0.48 |
| ▸ | ADA | P00813 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5182343 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL5163143 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL3727546 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL937118 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL8791673 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL6935273 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL6440905 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL509237 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL6884830 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL6884009 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081688-A2 | MRNA THERAPEUTIC COMPOSITIONS | NUTCRACKER THERAPEUTICS, INC. (US) | 2024-04-18 | — | — | WO | disclosed |
| EP-2633067-B1 | LUMINOPHORE-LABELED MOLECULES COUPLED WITH PARTICLES FOR MICROARRAY-BASED ASSAYS | CAPITALBIO TECH CORPORATION (CN) | 2023-06-28 | — | — | EP | disclosed |
| WO-2023101952-A1 | MODIFIED 5' UTR | NUTCRACKER THERAPEUTICS, INC. (US) | 2023-06-08 | — | — | WO | disclosed |
| CN-115956003-A | mRNA therapeutic nanoparticles | 胡桃钳医疗公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-115837014-A | Polynucleotides encoding relaxin | 摩登纳特斯有限公司 | 2023-03-24 | — | — | CN | disclosed |
| EP-4149506-A1 | POLYNUCLEOTIDES COMPRISING AN ANTIGENIC PAYLOAD | Nutcracker Therapeutics, Inc. (US) | 2023-03-22 | — | — | EP | disclosed |
| US-20230023741-A1 | MULTIPLEXED DIAGNOSTIC DETECTION APPARATUS AND METHODS | HANDYLAB, INC. | 2023-01-26 | — | — | US | disclosed |
| CN-115583950-A | Method for modifying purine Compounds and 6-position acylpurine Compounds | 鲁东大学 | 2023-01-10 | — | — | CN | disclosed |
| US-11453906-B2 | Multiplexed diagnostic detection apparatus and methods | HANDYLAB, INC. (US) | 2022-09-27 | — | — | US | disclosed |
| CN-109640962-B | Polynucleotides encoding relaxin | 摩登纳特斯有限公司 | 2022-07-19 | — | — | CN | disclosed |
| EP-0651759-A1 | NOVEL 2'-O-ALKYL NUCLEOSIDES AND PHOSPHORAMIDITES PROCESSES FOR THE PREPARATION AND USES THEREOF | ISIS PHARMACEUTICALS, INC. (US) | 1995-05-10 | — | — | EP | disclosed |
| WO-1994002501-A1 | NOVEL 2'-O-ALKYL NUCLEOSIDES AND PHOSPHORAMIDITES PROCESSES FOR THE PREPARATION AND USES THEREOF | ISIS PHARMACEUTICALS, INC. (US) | 1994-02-03 | — | — | WO | disclosed |
| WO-1993008296-A1 | OLIGONUCLEOTIDES HAVING CHIRAL PHOSPHORUS LINKAGES | ISIS PHARMACEUTICALS, INC. (US) | 1993-04-29 | — | — | WO | disclosed |
| EP-0257488-B1 | Novel diaminopyrimido[4,5-d]pyrimidine glycoside and glycotide and process | WARNER-LAMBERT COMPANY (US) | 1992-04-29 | — | — | EP | disclosed |
| EP-0245913-B1 | Process for preparing 6,7-dihydro-5,8-dimethyl-9-fluoro-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid | RIKER LABORATORIES, INC. (US) | 1992-03-25 | — | — | EP | disclosed |
| WO-1990008147-A1 | PURINE NUCLEOSIDES, PROCESS FOR PRODUCING THEM, AND DRUGS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1990-07-26 | — | — | WO | disclosed |
| EP-0257488-A2 | Novel diaminopyrimido[4,5-d]pyrimidine glycoside and glycotide and process | WARNER-LAMBERT COMPANY (US) | 1988-03-02 | — | — | EP | disclosed |
| EP-0245913-A1 | Process for preparing 6,7-dihydro-5,8-dimethyl-9-fluoro-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid | RIKER LABORATORIES, INC. (US) | 1987-11-19 | — | — | EP | disclosed |
| EP-0233493-A2 | Process for producing ribonucleosides | Yamasa Shoyu Kabushiki Kaisha (JP) | 1987-08-26 | — | — | EP | disclosed |
| US-4014769-A | ACETYLATION OF 9-B-D-RIBOFURANOSYLPURINE | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) | 1977-03-29 | — | — | US | disclosed |