Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | STAT6 | P42226 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | PYGL | P06737 | 9/20 | 0.48 |
| ▸ | ADA | P00813 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2914679 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL5182343 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL5163143 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL3727546 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL937118 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL8791673 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL6935273 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL509237 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL6884830 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL6884009 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572097-A2 | NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION | GENELABS TECHNOLOGIES, INC. (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004028481-A2 | NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION | GENELABS TECHNOLOGIES, INC. (US) | 2004-04-08 | — | — | WO | disclosed |