Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.42 |
| ▸ | PPARD | Q03181 | 6/20 | 0.42 |
| ▸ | PPARA | Q07869 | 6/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30543580 | 1.00 | SLC22A6 (0.55) | SLC22A6ALDH1A1LMNATSHRNFKB1 | |
| SCHEMBL30543592 | 0.95 | LMNA (0.55) | SLC22A6ALDH1A1LMNATSHRNFKB1 | |
| SCHEMBL1408433 | 0.84 | — | — | |
| SCHEMBL29264685 | 0.84 | — | — | |
| SCHEMBL23829487 | 0.84 | — | — | |
| SCHEMBL10880550 | 0.84 | ALDH1A1 (0.73) | ALDH1A1TSHRPMP22 | |
| SCHEMBL26250428 | 0.84 | ALDH1A1 (0.73) | ALDH1A1TSHRPMP22 | |
| Adipic Acid SCHEMBL8071355 | 0.79 | LMNA (0.61) | SLC22A6ALDH1A1LMNATSHRNFKB1 | |
| Glutarate SCHEMBL28291706 | 0.78 | SLC22A6 (0.79) | SLC22A6ALDH1A1LMNATSHRNFKB1 | |
| Glutarate SCHEMBL5712395 | 0.78 | SLC22A6 (0.79) | SLC22A6ALDH1A1LMNATSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486818-A | N-phenyl thiotriazinone derivative and preparation method and application thereof | 贵州大学 | 2024-02-02 | — | — | CN | disclosed |