Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13132432 | 0.95 | GPR119 (0.50) | GPR119GRM5KDM4EMAPTTHRB | |
| SCHEMBL31180134 | 0.83 | GPR119 (0.49) | GPR119KDM4EMAPTTHRB | |
| SCHEMBL21245809 | 0.83 | ALOX5AP (0.50) | GPR119KDM4EMAPTTHRBCNR1 | |
| SCHEMBL29148539 | 0.80 | CNR2 (0.49) | GPR119KDM4EMAPTTHRBCNR1 | |
| SCHEMBL30849193 | 0.80 | CNR2 (0.49) | GPR119KDM4EMAPTTHRBCNR1 | |
| SCHEMBL25324271 | 0.79 | CNR2 (0.49) | GPR119KDM4EMAPTTHRBCNR1 | |
| SCHEMBL31097541 | 0.79 | CNR2 (0.49) | GPR119KDM4EMAPTTHRBCNR1 | |
| SCHEMBL13132440 | 0.79 | GPR119 (0.48) | GPR119KDM4EMAPTTHRB | |
| SCHEMBL4178267 | 0.78 | GPR119 (0.50) | GPR119GRM5KDM4EMAPTTHRB | |
| SCHEMBL4174643 | 0.78 | SSTR4 (0.48) | GPR119KDM4EMAPTTHRBCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447449-A | PARP1 inhibitor and application thereof | 南京圣和药业股份有限公司 | 2024-01-26 | — | — | CN | disclosed |