Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 7/20 | 0.39 |
| ▸ | ALPL | P05186 | 9/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | RPA1 | P27694 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6110252 | 0.78 | HCAR3 (0.47) | HCAR3ALPLCA12RPA1TP53 | |
| SCHEMBL6110152 | 0.77 | HCAR3 (0.45) | HCAR3ALPLCA12RPA1TP53 | |
| SCHEMBL6110120 | 0.76 | HCAR3 (0.42) | HCAR3ALPLCA12RPA1TP53 | |
| SCHEMBL1815529 | 0.76 | HCAR2 (0.53) | HCAR3ALPLCA12TP53HCAR2 | |
| SCHEMBL6110959 | 0.73 | ALPL (0.46) | HCAR3ALPLCA12RPA1TP53 | |
| SCHEMBL16763221 | 0.73 | HCAR3 (0.50) | HCAR3ALPLCA12RPA1TP53 | |
| SCHEMBL6109961 | 0.72 | HCAR3 (0.41) | HCAR3ALPLCA12RPA1TP53 | |
| SCHEMBL6109364 | 0.72 | HCAR3 (0.44) | HCAR3ALPLCA12RPA1TP53 | |
| SCHEMBL26054148 | 0.71 | TP53 (0.47) | HCAR3ALPLCA12RPA1TP53 | |
| SCHEMBL6110374 | 0.71 | HCAR3 (0.40) | HCAR3ALPLCA12RPA1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117136052-A | CDK inhibitors and methods of use thereof | 传达治疗有限公司 | 2023-11-28 | — | — | CN | disclosed |