Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.33 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.32 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29149006 | 0.87 | SIGMAR1 (0.39) | — | |
| SCHEMBL29213779 | 0.79 | EPHX2 (0.44) | ALDH1A1TSHRKDM4EGAAHSD17B10 | |
| SCHEMBL29213781 | 0.79 | EPHX2 (0.44) | ALDH1A1TSHRKDM4EGAAHSD17B10 | |
| SCHEMBL29213768 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TSHRKDM4EGAAHSD17B10 | |
| SCHEMBL29213871 | 0.75 | ALDH1A1 (0.49) | ALDH1A1TSHRKDM4EGAAHSD17B10 | |
| SCHEMBL29149063 | 0.73 | ALDH1A1 (0.47) | ALDH1A1TSHRKDM4EGAAHSD17B10 | |
| SCHEMBL29058225 | 0.73 | ALDH1A1 (0.47) | ALDH1A1TSHRKDM4EGAAHSD17B10 | |
| SCHEMBL29213782 | 0.73 | ALDH1A1 (0.44) | ALDH1A1TSHRKDM4EGAAHSD17B10 | |
| SCHEMBL29213835 | 0.72 | TSHR (0.43) | ALDH1A1TSHRKDM4EGAAHSD17B10 | |
| SCHEMBL16400755 | 0.71 | KDM4E (0.44) | ALDH1A1TSHRKDM4EGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500499-A | Substituted indole compounds and methods of use thereof | 奇努克治疗公司 | 2024-02-02 | — | — | CN | disclosed |