Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | AKT1 | P31749 | 2/20 | 0.57 |
| ▸ | IKBKB | O14920 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.54 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.52 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL623886 | 0.80 | AKR1C3 (0.57) | CYP19A1KDM4ECYP3A4HPGDMEN1 | |
| Vogelin C SCHEMBL31238207 | 0.77 | PDE4D (0.71) | CYP19A1KDM4ECYP3A4AKT1IKBKB | |
| Demethylmoracin I SCHEMBL6818913 | 0.76 | CYP19A1 (1.00) | CYP19A1AKT1PTPN1HIF1AEPAS1 | |
| SCHEMBL29149093 | 0.75 | HPGD (0.70) | CYP19A1KDM4ECYP3A4HPGDMEN1 | |
| SCHEMBL4650047 | 0.75 | HPGD (1.00) | CYP19A1KDM4ECYP3A4HPGDMEN1 | |
| SCHEMBL15360894 | 0.73 | VKORC1 (0.57) | CYP19A1KDM4ECYP3A4HPGDMEN1 | |
| SCHEMBL16670860 | 0.73 | HPGD (0.81) | CYP19A1KDM4ECYP3A4HPGDMEN1 | |
| SCHEMBL29370223 | 0.73 | HPGD (0.81) | CYP19A1KDM4ECYP3A4HPGDMEN1 | |
| SCHEMBL30637443 | 0.73 | AKT1 (1.00) | CYP19A1KDM4EHPGDAKT1ABCG2 | |
| SCHEMBL27013441 | 0.73 | AKT1 (1.00) | CYP19A1KDM4EHPGDAKT1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447402-A | Aromatic hydrocarbon receptor modulator compound, and preparation method and application thereof | 德明药泰生物技术（深圳）有限公司 | 2024-01-26 | — | — | CN | disclosed |