Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 1.00 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.71 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.69 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.62 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.56 |
| ▸ | BACE1 | P56817 | 2/20 | 0.56 |
| ▸ | TYR | P14679 | 1/20 | 0.56 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.56 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.56 |
| ▸ | FASN | P49327 | 2/20 | 0.56 |
| ▸ | MGAM | O43451 | 1/20 | 0.56 |
| ▸ | IDH1 | O75874 | 1/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SI | P14410 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30637443 | 1.00 | AKT1 (1.00) | AKT1ABCG2PDE4DPTPN1HPGD | |
| SCHEMBL24075639 | 0.91 | AKT1 (0.83) | AKT1ABCG2PDE4DPTPN1HPGD | |
| SCHEMBL29629602 | 0.87 | ABCG2 (0.83) | AKT1ABCG2PDE4DPTPN1HPGD | |
| SCHEMBL4834777 | 0.87 | ABCG2 (0.83) | AKT1ABCG2PDE4DPTPN1HPGD | |
| SCHEMBL30410935 | 0.83 | ABCG2 (1.00) | AKT1ABCG2PDE4DPTPN1HPGD | |
| SCHEMBL20954091 | 0.83 | ABCG2 (1.00) | AKT1ABCG2PDE4DPTPN1HPGD | |
| SCHEMBL4836863 | 0.82 | AKT1 (1.00) | AKT1ABCG2PDE4DPTPN1HPGD | |
| Cudraflavone C SCHEMBL26679530 | 0.82 | PDE4D (1.00) | AKT1ABCG2PDE4DPTPN1HPGD | |
| SCHEMBL31691719 | 0.82 | AKT1 (1.00) | AKT1ABCG2PDE4DPTPN1HPGD | |
| SCHEMBL26621014 | 0.82 | ABCG2 (0.81) | AKT1ABCG2PDE4DPTPN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240016777-A1 | COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 2024-01-18 | — | — | US | disclosed |
| US-20240016777-A1 | COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240016777-A1 | COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS | THPO, SERPINB1, SERPINC1 | AKT1 4428/4885ABCG2 1601/4885PDE4D 4230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.